The Velocity Manifesto
Seven principles for moving from more activity to more informative decisions.
ReadA working thesis about how life sciences can turn better evidence into better decisions.
Velocity is a vector: speed with direction. In this project, it is a deliberate metaphor for connecting models, measurements and computation to the outcomes we want to improve.
There is no universal “Velocity score,” and no claim that this framework has already increased industry productivity.
Start with the seven principlesAverage velocity = displacement / elapsed time.
Speed with direction, not speed plus direction.The chosen destination is east. Move the controls and watch what happens to the velocity component toward it.
Moving away. More speed increases movement in the wrong direction.
A physical vector demonstration, not a drug-development simulator or a prediction of success.
Seven principles for moving from more activity to more informative decisions.
ReadA practical distinction between a measured response and a meaningful benefit.
ReadThe right model is the one that can inform the decision you actually face.
ReadWhy the Future of Medicine Isn't About Moving Faster
ReadWhat would improve our confidence in efficacy, safety and responder biology?
Which early measurements connect to meaningful human outcomes?
How do we align human-relevant evidence with the specific claim being made?